Influenza viruses

With thorough expertise in the field of influenza virus production systems, VirNext offers panoply of solutions and deliverables, ranging from specific vaccine antigens to whole infectious or inactivated viruses. Various human and animal influenza strains and several production systems are proposed. 


 

Production systems

  • Adherent cells in flasks,  hyperflasks or microcarriers
  • Cells in suspension
  • Embryonated hen eggs
  • Custom-adapted production systems

Influenza viruses

  • Influenza A (H1N1 and H3N2) and  B strains
  • Influenza avian strains
  • Pandemic, seasonal and vaccine reference strains

Deliverables

  • Viral supernatant (up to several liters)
  • Concentrated virus
  • Highly purified virus (~99%)
  • Inactivated virus
  • Quantified vaccine antigen split (single radial immuno-diffusion assay)

 


VirNext provides complete characterization of each deliverable (including complete genome sequence), with quantitatively and qualitatively evaluated batches (see Influenza Services). Packaging is custom made, including high concentration/volume viral stocks or small-volume aliquots, depending on the customer’s needs. In-house storage at -80°C is also possible. 

 


Other Viruses

VirNext has an extensive virus collection, including respiratory syncitial virus (RSV), parainfluenza virus (PIV), adenovirus, rhinovirus and human metapneumovirus (hMPV) among others. Please contact us for more information on production and evaluation services. 

Quality Control

 

  • Mycoplasma and bacteria detection assays
  • Molecular detection of contaminants by specific qPCR for different micro-organisms
  • Genetic characterization and purity by Sanger and next-generation sequencing